Current Issue : January - March Volume : 2016 Issue Number : 1 Articles : 10 Articles
A three year old doberman dog was referred to the clinic with a history of purulent discharges which were noticed on the back region. Dog showed erosions, desquamation of skin with purulent exudates all over the dorsum region. Cytological examination of smears from the skin lesions revealed presence of mixed bacterial infection, presence of more number of neutrophils and free form parasitic infection. Condition was diagnosed as actinic dermatitis and treated with external application of povidone iodine and gentamicin ointment on the day of presentation. Dog was treated with tab. Enrofloxacin @ 5 mg/kg body weight, PO, capsule vitamin E 200 mg PO, along with daily dressing of skin lesions with ointment gentamicin, calamine, allontoin and vitamin E lotion. The skin lesions resolved after two weeks of therapy and complete healthy scar formation was noticed....
Objective. To establish signalment and phenomenology of canine idiopathic head tremor syndrome (IHTS), an episodic head\nmovement disorder of undetermined pathogenesis. Design. Retrospective case series. Animals. 291 dogs with IHTS diagnosed\nbetween 1999 and 2013. Procedures. Clinical information was obtained from an online community of veterinary information\naggregation and exchange (Veterinary Information Network, 777 W Covell Boulevard, Davis, CA 95616) and conducted with\ntheir approval. Information on breed, sex, age of onset, tremor description, mentation during the event, effect of distractions and\ndrugs, diagnostics, presence of other problems, and outcome was analyzed. Results. IHTS was found in 24 pure breeds. Bulldogs,\nLabrador Retrievers, Boxers, and Doberman Pinschers comprised 69%; mixed breeds comprised 17%. Average onset age was 29\nmonths (range: 3 months to 12 years). First episode occurred before 48 months of age in 88%. Vertical (35%), horizontal (50%),\nand rotational (15%) movements were documented. Possible trigger events were found in 21%. Mentation was normal in 93%.\nDistractions abated the tremor in 87%. Most dogs did not respond to antiepileptic drugs. Conclusions and Clinical Relevance. This\nretrospective study documents IHTS in many breeds including Labrador Retrievers, Boxers, and mixed breeds....
A cross-sectional study was carried out in four indigenous communities of Costa Rica to detect presence and prevalence of Babesia\ncaballi and Theileria equi and to investigate factors associated with presence of these hemoparasites. General condition of horses\n(...
This study tested the impact of moxidectin at peripartum on nematode fecal egg count (FEC) and clinical parameters on ewes in\nthe high altitude tropical Andes of Colombia. FEC and clinical evaluations were performed on 9 occasions in 43 naturally infected\newes before and during gestation and after lambing. Moxidectin (Mox, 200 ...
This study aimed to evaluate the ability of a panel of lectins to inhibit the ability of Pasteurella multocida to adhere to and affect the\nrabbit respiratory epithelium. Nasal septa from rabbit fetuses were cultured with various lectins before the addition of P. multocida.\nThe percentage of bacteria adhering to the epithelium was evaluated semiquantitatively by indirect immunoperoxidase (IIP)\nstaining.The goblet cells (GCs)were counted in semithin sections stained with toluidine blue and served as the main morphological\ncriterion to evaluate the inhibitory effect of the lectins. The lectins PNA, WGA, RCA120, and DBA significantly inhibited the\nadhesion of P. multocida to the ciliated epithelium (...
The aims were as follows: (1) to evaluate the effects at 48 and 96 h of two concentrations (25 and 50%) of leukocyte and platelet-rich\ngel (L-PRG) and pure PRG (P-PRG) supernatants on the production/degradation in normal equine synovial membrane explants\n(SME) of platelet derived growth factor isoform BB, transforming growth factor beta-1, tumor necrosis factor alpha, interleukin\n(IL-) 4 (IL-4), IL-1 receptor antagonist (IL-1ra), and hyaluronan (HA) synthesis and (2) to correlate these molecules with their\nrespective PRG supernatant treatments. SME from 6 horses were cultured for 96h with L-PRG and P-PRG supernatants at 25\nand 50% concentrations, respectively. SME culture media were changed each 48 h and used for determination by ELISA of the\nmolecules, which were also determined in synovial fluid. 25% L-PRG supernatant produced a sustained release over time of IL-1ra\nand a gradual release of HA, whereas 50% L-PRG supernatant produced a sustained increase over time of IL-4 and HA. 50% PPRG\nsupernatant produced an increased and sustained production of IL-1ra and IL-4. The cellular composition and the articular\nconcentration (volume) of a platelet-rich plasma preparation could affect the anti-inflammatory and anabolic joint responses in\nhorses with osteoarthritis....
Successful veterinary treatment of animals requires owner adherence with a prescribed treatment plan. The aim of our study was\nto evaluate and compare the level of adherence of the owners of patients presented for behavioural, cardiological, urological, and\noncological problems. At the end of the first examination, each owner completed a questionnaire. Then, the owners were called four\ntimes to fill out another questionnaire over the phone. With regard to the first questionnaire, statistically significant data concern\nbehavioral medicine and cardiology. In the first area the owner�s worry decreases during the follow-up and the number of owners\nwho would give away the animal increases. In cardiology, owners who think that the pathology harms their animal�s quality of life\ndecreased significantly over time. With regard to the 9 additional follow-up questions, in behavioural medicine and urology the\nowner�s discomfort resulting from the animal�s pathology significantly decreases over time. Assessment of adherence appears to\nbe an optimal instrument in identifying the positive factors and the difficulties encountered by owners during the application of a\ntreatment protocol....
A study was conducted to determine the serotypes of foot-and-mouth disease viruses (FMDV) circulating in African buffaloes\n(Syncerus caffer) from selected areas in Zambia. Sera and probang samples were collected between 2011 and 2012 and analysed for\npresence of antibodies against FMDV while probang samples were used to isolate the FMDV by observing cytopathic effect (CPE).\nSamples with CPE were further analysed using antigen ELISA. High FMD seroprevalence was observed and antibodies to all the\nthree Southern African Territories (SAT) serotypes were detected in four study areas represented as follows: SAT2 was 72.7 percent;\nSAT1 was 62.6 percent; and SAT3 was 26.2 percent. Mixed infections accounted for 68.6 percent of those that were tested positive.\nFor probang samples, CPE were observed in three of the samples, while the antigen ELISA results showed positivity and for SAT1\n(...
An adult buffalo was suffering with chronic mastitis since one month. Up on clinical examination, one of the quarters (RH) was hot and painful and others were normal in size with pyrexia (103.5°F), tachycardia (92/min) and tachypnea (33/min). The milk from the affected quarter was discolored and watery in consistency. Milk from the affected hind teats showed positive to the California mastitis test. The antibiotic sensitivity patterns of the culture isolates from the RH quarter were resistant to amoxicillin, streptomycin, trimethoprim, cephalexin, ampicillin, enrofloxacin, ciprofloxacin, oxytetracycline and gentamicin. Isolates from the LH were resistant to amoxicillin, streptomycin, trimethoprim, enrofloxacin, oxytetracycline and gentamicin. Present buffalo was successfully treated with parentral ceftiofur sodium, intra mammary infusions along with supportive therapy....
This study was to establish a systemic C. parapsilosis infection model in immunosuppressed ICR mice induced by cyclophosphamide\nand evaluate the antifungal efficiency of fluconazole. Three experiments were set to confirm the optimal infectious dose of C.\nparapsilosis, outcomes of infectious model, and antifungal efficiency of fluconazole in vivo, respectively. In the first experiment,\ncomparisons of survival proportions between different infectious doses treated groups showed that the optimal inoculum for C.\nparapsilosis was 0.9 Ã?â?? 105 CFU per mouse.The following experiment was set to observe the outcomes of infection at a dose of 0.9 Ã?â??\n105 CFU C. parapsilosis. Postmortem and histopathological examinations presented fugal-specific lesions in multi organs, especially\nin kidneys, characterized by inflammation, numerous microabscesses, and fungal infiltration.The CFU counts were consistent with\nthe histopathological changes in tissues. Th1/Th2 cytokine imbalance was observed with increases of proinflammatory cytokines\nand no responses of anti-inflammatory cytokines in sera and kidneys. In the last experiment, model based evaluation of fluconazole\nindicated that there were ideal antifungal activities for fluconazole at dosages of 10ââ?¬â??50 mg/kg/d.Data demonstrates that the research\nteam has established a systemic C. parapsilosis infection model in immunosuppressed ICR mice, affording opportunities for\nincreasing our understanding of fungal pathogenesis and treatment....
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